脱炭酸とは、物質を加熱してカルボキシル基を除去する化学的プロセスである。カンナビス（医療用）にはテトラヒドロカンナビノール酸（THCA）が含まれており、脱炭酸によって精神作用のあるテトラヒドロカンナビノール分子（THC）に変換することができます。これは、医薬品や娯楽用カンナビス（医療用）の製造アプリケーションに不可欠なものです。
PF460は、製薬業界向けのカンナビス（医療用）の乾燥と脱炭酸のために特別に設計されており、最大200℃までの運転が可能です。この範囲であれば、乾燥と脱炭酸の両方の工程で最適な温度を切り替えて使用することができます。
このオーブンは、温度均一性の維持と庫内の水分抽出に役立つ2つの大型循環ファンを備え、必要に応じて風量を調整できる手動式の吸気・排気ダンパーを備えています。棚板は4枚ですが、最大13枚まで取り付け可能で、460リットルの容量を最大限に活用することができます。
PF460は、水分除去用の排気ファン、窒素ガスシステム、各種温度コントローラーなど、さまざまなオプションが用意されています。また、米国市場向けに設計されたこのオーブンは、CSA/UL規格に適合しています。
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RETSCH is putting to use its full product portfolio of grinders, sieve shakers and sample dividers to help process and prepare cannabis samples. The sample preparation process needs to be adjustable to the considerable complexity of the various matrices. Whether the samples are gummy bears, brownies, candies, or cannabis flower, RETSCH can provide assistance in selecting the ideal instrument to meet the application requirements.
The Ultra Centrifugal Mill ZM 200 is ideally suited for quickly pulverizing fibrous samples like cannabis or hemp flower to grind sizes below 0.5 mm. The wide range of accessories includes distance sieves which allow for processing heat-sensitive samples. The use of a cyclone has a cooling effect on the sample and allows for grinding up to 4.5 l of sample
For pesticide analysis of oily, sticky samples like hemp, the required homogenization should be carried out in a cryogenic mill like RETSCH’s CryoMill. To transfer the pesticides from the sample into the organic phase, the mixture is agitated for 1 to 3 minutes, e.g. in a laboratory mill like the Mixer Mill MM 400.
To reliably quantify active components in cannabis, a representative sample needs to be extracted from the bulk. The GRINDOMIX GM 300 can homogenize up to 4 liter of plant material from which a small fraction is taken for analysis. Remnants of small twigs or resinous blossoms are no problem for this mill. The smaller model GRINDOMIX GM 200 quickly and efficiently homogenizes up to 700 ml sample material high in sugar or fat content, such as cannabis-infused cookies.
The high-performance Cutting Mill SM 300 is now available in a stainless steel 316L foodGrade version.This mill ensures reproducible particle size reduction without loss of cannabinoids or terpenes.
With a 150 l drum of 316L stainless steel the Drum Mill TM 500 is is also available in a 316L foodGrade version.
Applications within the cannabis industry benefit from an accurate particle size analysis. From seed to consumer product, the cannabis industry has different levels of processing with numerous exit points for final product. For example, if your desired product is consumable plant matter, you are not going to be concerned with the complicated steps of oil extraction.
One application is the measurement of spray dried powders which are created from nanoemulsions. By analyzing the dried powders, one determines the quality and uniformity of the particles to insure consistent and effective product. This is best performed by Microtrac Sync Dry Laser Diffraction instruments, which can measure dry powders from 0.25 to 2,000 microns.
Additionally, particle size analysis is critical for nanoemulsion creation from THC or CBD oil extracted from either cannabis or hemp. This product is commonly called “water-soluble” oil. Despite the misnomer, the oil is not made soluble. It is made into a stable nanoemulsion by reducing the size of the oil droplets to a level by which they are completely clear in a drink and stable on the shelf. The product is also made more bioavailable. In order to develop and continuously measure these processes, you will need a Dynamic Light Scattering particle size analyzer.
Dynamic Light Scattering is well suited for this application due to the measurement range of the instruments. The Microtrac NANOTRAC family of instruments have a particle size measurement rage of 0.3 nanometers to 10 micrometers. While there is overlap of the range from the Laser Diffraction particle size analyzers from Microtrac, experience has shown that this application is best suited for DLS analysis. The NANOTRAC family of analyzers allows for customization of analysis with the various configurations of internal well with Zeta potential analysis, external probe analysis, and cuvette-based analysis.
When it comes to particle size analysis of nanoemulsions, Microtrac has instrumentation which is suited to your needs and preferences.
